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Dr. Brooke Show #462 Can HRT Make You Gain Weight?

October 23, 2026

Some of the more frustrating symptoms of midlife hormone decline and perimenopause is stubborn fat loss, weight gain, and fat redistribution around the midsection. HRT is often part of what’s promoted to manage these metabolic changes, and many women expect to lose weight when they start it. While replacing hormones like estrogen, progesterone and testosterone can help with fat loss and muscle gain, some women will experience weight gain for a variety of reasons when they begin using hormones. In this episode I cover the five biggest reasons this happens and what you can do about it.

 

Resources mentioned in this episode:

Progesterone cycling: Episode #444 – Should You Be Cycling Your HRT?

Better by Dr. Brooke: adapt + cope – optimal adaptogen blend

Better by Dr. Brooke: better + b active – activated b complex

Better by Dr. Brooke: better + magnesium – magnesium glycinate complex

 

Grab the Midlife Is More Than HRT guide free right here if, like me, midlife didn’t feel quite like you expected. And be sure to listen to episodes #438 and #439, which were all about the mess that midlife can be, and my 3G + 4R process to tackle it!

 

Stuff I Know You Will Love

If you are looking for an expert prescriber for HRT during your perimenopause or menopause journey but are at odds with your local provider being a bit behind current best practices or you simply can’t find anyone near you to help, it is MIDI to the rescue! I’ve worked with a number of telehealth services in my search for providers that are up to date on modern menopause medicine, have great customer service, and are licensed in all 50 states and I’m so thrilled to have found my provider with MIDI. If you too need help with getting HRT please use this link bit.ly/drbrookemidi to try MIDI with no membership fees and insurance billing available.

 

Be sure you connect with me in my FREE PRIVATE Facebook group: Hormones & Happiness with Dr. Brooke where other amazing, like-minded women like YOU are already hanging out! Join us!

 

Follow Dr. Brooke on Instagram and get signed up for my awesome emails here. Seriously, I write really great emails, or so 1000s of women tell me and I’d like to send you one too.


To work with Dr. Brooke click here and if you loved this episode, please leave a review!

Dr Brooke Kalanick, ND, MS, LAc

Dr Brooke Kalanick is a naturopathic and functional medicine physician specializing in thyroid issues, autoimmunity, histamine intolerance, and women's hormone issues including PCOS, perimenopause, endometriosis and infertility. She is the best selling co-author of HANGRY: Balance Your Hormones & Restore Your Joy in 5 Simple Steps. She is also the host of the Dr Brooke Show podcast. To learn more about Dr Brooke click here.

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